Ghrelin
Norepinephrine (NE)
- functions
- regulation of expression
- consequences of overexpression
- consequences of underexpression
- signalling pathways
- structure
Function
Ghrelin is an endogenous ligand of growth hormone secretagogue receptor in the pituitary and hypothalamus. It is released during periods of fasting to increase GH secretion.
It also acts on the liver to...
Regulation of Expression
Ghrelin is produced by gastric neuroendocrine cells.
Consequences of Overexpression
Overexpression of PRL (hyperprolactinemia) can lead to galactorrhea
Consequences of Underexpression
Signalling Pathways
Both PRL and GH have similiar affinities for the PRL receptor.
Structure
Prolactin is a 199 amino acid hormone with 16% homology to growth hormone.