Renal Biopsy
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Introduction
Indications
Biopsy is commonly done when glomerular problems are likely, or when acute renal failure is unexplained.
Procedure
Local anesthetic is used.
Analysis
- Light Microscopy
- Immunofluorescence
- Electron Microscopy
Light Microscopy
Examine glomeruli, tubules, and interstitium.
Look for areas devoid of tubules, suggesting scarring
PAS Stain demonstrates cellularity.
Silver staining..
Immunoflorescence
IgA - can depict IgA nephropathy
IgG
Electron Microscopy
Potential Adverse Effects
Percutaneous biopsy is most commonly done and is relatively safe, though can lead to hematuria, hematoma, vascular lasceration and AV fistula formation, and biopsy of other tissues.
Contraindications
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Additional Resources
Topic Development
created: DLP, Aug 09
authors: DLP, Aug 09
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