Autism Spectrum Disorder

 

 

Causes and Risk Factors

 

 

 

 

 

Signs, Symptoms, and Diagnosis

There is a triad of symptoms in autism.

 

social interaction impairments

communication interaction impairments

repetitive, restrictive, or stereotyped behaviours

decision-making

 

 

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Pathophysiology

 

Genetic and Chromosomal Abnormalities

18% of people with fragile X have autism, while 5% of people with autism have fragile X. Other chromosomal abnormalities are seen in 5% of people with autism.

The 5-HT transporter or receptor gene appears affected in some people.

 

Metabolism

PKU, histidinemia, Lesch Nyhan Syndrome

 

Infections

rubella, CMV, herpes simplex, HIV

 

 

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Treatments

 

 

 

 

 

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Consequences and Course

 

 

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The Patient

 

 

 

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Health Care Team

 

 

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Community Involvement

 

 

 

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References