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Thrombocytosis
Thrombocytosis is the rarest of all the myeloproliferative disorders.
- signs and symptoms
- diagnosis
- types of thrombocytosis
- pathophysiology
- causes and risk factors
- treatments
- course
Signs and Symptoms
Diagnosis
- abnormal platelet number and function
Types of Thrombocytosis
Primary
clonal problem in megakaryocytes
Secondary
or reactive. nonclonal.
- low iron (likely cross talk of elevated EPO on the TPO receptors)
- postsplenectomy
- inflammation
- cancer
physiologic
- exercise
- parturation
Pathophysiology
Causes and Risk Factors
Treatments
Course
Small risk of transformation to AML, polycythemia vera, or myelofibrosis.
The overall life expectancy is near normal.