Dermatitis Herpatiformis

 

 

Causes and Risk Factors

 

 

 

 

 

Signs, Symptoms, and Diagnosis

Often diagnosis is profoundly delayed

 

  • history
  • physical exam
  • lab investigations
  • diagnostic imaging

History

INTENSE pruitus

almost everyone has mild celiac disease

Physical Exam

 

Elbows, knees, lumbar spine

 

Lab Investigations

 

Tissue transglutaminase is almost always positive

Diagnostic Imaging

 

 

 

 

 

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Pathophysiology

 

autoimmune IgA mediated

neutrophils

 

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Treatments

 

Refractory to steroids.

 

Dapsone 100mg po OD, works within 24 hours. Can cause leukopenia, hypersensivity, and peripheral neuropathy (long term use).

 

Gluten-free diet takes 6 monhts.

 

 

 

 

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Consequences and Course

 

 

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Resources and References