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Inhibitors of Labour (Tocolytics)

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Introduction

Prostaglandin synthetase inhibitors are used to stop preterm labour.
Indomethacin inhibits phospholipase A2 and is also used as a tocolytic.
Oxytocin antagonists (antosiban) has been developed as a tocolytic but is not available in Canada

Indomethicin is an NSAID which is used to maintain suppression of labour

Calcium channel blockers (ie nifedipine)